Abstract

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During the ongoing pandemic of coronavirus disease 2019 (COVID-19), sickle cell disease (SCD) has been seen to be both a possible protective and an adverse prognostic factor1-3.
So far, there have been few case reports of COVID-19 leading to the diagnosis of sickle cell trait or SCD4 and, to our knowledge, none in the pediatric population.
Here we describe the first two infants in whom a severe SARS-CoV-2 infection revealed a hidden condition of SCD. [ … ]

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Authors

Emilia Parodi - “Regina Margherita” Children’s Hospital, "AOU Città della Salute e della Scienza di Torino", Turin, Italy

Vincenzo Voi - Department of Clinical and Biological Sciences, University of Turin, Turin, Italy

Barbara Vania - Department of Paediatric and Public Health Sciences, Postgraduate School of Paediatrics, University of Torino, Turin, Italy

Pietro Lonardi - Department of Paediatric and Public Health Sciences, Postgraduate School of Paediatrics, University of Torino, Turin, Italy

Paola Saracco - “Regina Margherita” Children’s Hospital, "AOU Città della Salute e della Scienza di Torino", Turin, Italy

Annalisa Longobardo - “Regina Margherita” Children’s Hospital, "AOU Città della Salute e della Scienza di Torino", Turin, Italy

Sergio Grassitelli - “Regina Margherita” Children’s Hospital, "AOU Città della Salute e della Scienza di Torino", Turin, Italy

Licia Peruzzi - “Regina Margherita” Children’s Hospital, "AOU Città della Salute e della Scienza di Torino", Turin, Italy

Carlo Scolfaro - “Regina Margherita” Children’s Hospital, "AOU Città della Salute e della Scienza di Torino", Turin, Italy

Antonio Piga - Department of Clinical and Biological Sciences, University of Turin, Turin, Italy

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