Abstract

We report the case of a woman with trisomy 9 who showed atypical, mixed-field agglutination of ABO blood type. Her red blood cells showed strong agglutination with anti-A monoclonal antiserum and atypical mixed-field agglutination with anti-B monoclonal antiserum. The results of the genotyping of her father and mother revealed A101/B101 and O01/O02, respectively; however, only B101/O01 was detected in the patient because of the characteristics of the test method used. Multiplex analysis would help in understanding the pathophysiology of abnormal findings; nevertheless, careful data interpretation is required.

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Authors

Sena Fujii - Department of Blood Transfusion, Kyoto Prefectural University of Medicine, Kyoto, Japan

Yuji Shimura - Department of Blood Transfusion, Kyoto Prefectural University of Medicine, Kyoto, Japan

Keiichi Shigehara - Department of Pediatrics, Ayabe City Hospital, Kyoto, Japan

Yuji Sasada - Department of Blood Transfusion, Kyoto Prefectural University of Medicine, Kyoto, Japan

Tohru Inaba - Department of Infection Control & Laboratory Medicine, Kyoto, Japan

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