Original article

Blood Transfusion - 1 2022 (January-February)

Promoting physical activity in people with haemophilia: the MEMO (Movement for persons with haEMOphilia) expert consensus project


Key words: haemophilia, physical activity, sports, recommendations
Publication Date: 2021-10-15


Regular physical activity can increase joint stability and function, reduce the risk of injury, and improve quality of life of people with haemophilia (PwH). However, a recent review of the literature shows that appropriate physical activity and sport are not always promoted enough in the overall management of PwH. A group of Italian experts in haemophilia care undertook a consensus procedure to provide practical guidance on when and how to recommend physical exercise programmes to PwH in clinical practice. Three main topics were identified –haemophilia and its impact on movement, physical activity recommendations for PwH, and choice and management of sports activity in PwH– and ten statements were formulated. A modified Delphi approach was used to reach a consensus. The group also created practical tools proposing different physical activities and frequencies for different age groups, the Movement Pyramids, to be shared and discussed with patients and caregivers.  In conclusion, in the opinion of the working group, physical activity can be considered as a low-price intervention that can prevent/reduce the occurrence of chronic diseases and should be further encouraged in PwH to obtain multiple physical and psychological benefits. Future research should include prospective studies focusing on participation in sports, specific risk exposure and clinical outcomes.



Chiara Biasoli - Unit of Transfusion Medicine and Centre for Inherited Bleeding Disorders, “M. Bufalini” Hospital, Cesena, Italy

Erminia Baldacci - Haematology, “Umberto I” Policlinico, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

Antonio Coppola - Regional Reference Centre for Inherited Bleeding Disorders, University Hospital of Parma, Parma, Italy

Raimondo De Cristofaro

Matteo N.D. Di Minno - Department of Translational Medical Sciences, “Federico II” University, Naples, Italy

Giuseppe Lassandro - Department of Biomedical Science and Human Oncology-Paediatric Unit, “Aldo Moro” University of Bari, Italy

Silvia Linari - Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Florence, Italy

Maria E. Mancuso - Centre for Thrombosis and Haemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy

Mariasanta Napolitano - Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo and Haematology Unit, "P. Giaccone" University Hospital, Palermo, Italy

Angiola Rocino - Haemophilia and Thrombosis Centre, Haematology, Ospedale del Mare, Naples, Italy

on behalf of the MEMO Study Group (Appendix I) - The Members of the MEMO Study Group are listed in Appendix 1

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