Abstract

“Missense mutations in PIEZO1, encoding the Piezo1 mechanosensor protein, define the Er red blood cell antigens” prepublished by Thornton’s team in Blood, in September 20221, is an excellent study showing that Piezo1, a protein of wide biological interest, is the carrier of three known antigens that did not fit into any known blood group system.

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Authors

Serelina Coluzzi - Special Immunohematology Unit, Immunohematology and Tranfusion Medicine Complex Unit, Policlinico Umberto I-Sapienza University, Rome, Italy

Nicoletta Revelli - Department of Transfusion Medicine and Hematology and Lombardy Regional Rare Blood Bank, IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

Barbara Baluce - Department of Transfusion Medicine and Hematology and Lombardy Regional Rare Blood Bank, IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

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