Position paper

Blood Transfusion 5-2018 (September-October)

Position Paper on laboratory testing for patients on direct oral anticoagulants. A Consensus Document from the SISET, FCSA, SIBioC and SIPMeL

Authors

Key words: DOAC, anticoagulation, thrombosis, consensus
Publication Date: 2017-09-13

Abstract

Although direct oral anticoagulants (DOAC) do not require dose-adjustment on the basis of laboratory test results, the measurement of their anticoagulant effect is useful in special situations. This position paper issued by the Italian Scientific Societies that are mainly involved in the management of patients on DOAC is aimed at providing guidance to care-givers on which tests should be used and the situations in which testing is useful. The guidance is based on the data from the literature so far available and/or on consensus among experts.

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Authors

Armando Tripodi - "Angelo Bianchi Bonomi" Haemophilia and Thrombosis Centre, Department of Clinical Sciences and Community Health, University of Milan and IRCCS Maggiore Hospital, Milan

Walter Ageno - Research Centre on Thromboembolic Diseases and Antithrombotic Therapies, Department of Clinical and Experimental Medicine, University of Insubria, Varese

Marcello Ciaccio - Section of Clinical Biochemistry and Clinical Molecular Medicine, Department of Biopathology and Medical Biotechnology, University of Palermo, Palermo

Cristina Legnani - Angiology and Blood Coagulation, University Hospital of Bologna, Bologna

Giuseppe Lippi - Section of Clinical Biochemistry, University of Verona, Verona

Cesare Manotti - Haemostasis Centre, Fidenza-Vaio Hospital, Fidenza

Rossella Marcucci - Department of Experimental and Clinical Medicine, University of Florence, Florence

Marco Moia - "Angelo Bianchi Bonomi" Haemophilia and Thrombosis Centre, Department of Clinical Sciences and Community Health, University of Milan and IRCCS Maggiore Hospital, Milan

Benedetto Morelli - SIBioC Haemostasis and Thrombosis Study Group, Milan

Daniela Poli - Thrombosis Centre, "Careggi" University Hospital, Florence

Agostino Steffan - Translational Research Department, Cancer Referral Centre, Aviano

Sophie Testa - Department of Laboratory Medicine, Haemostasis and Thrombosis Centre, Hospital Institutes, Cremona, Italy

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