Efficacy of platelet-rich plasma as conservative treatment in orthopaedics

Abstract

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Platelet rich plasma therapy (PRP) involves removing autologous blood and enriching the platelet content prior to injection at sites of injury. Clinicians in Italy introduced PRP in 1987 for autologous transfusion for cardiac surgery patients1. Later, orthopaedic surgeons adapted PRP to promote adherence of bone graft material and to prevent tissue drying2. Clinicians developed PRP as a treatment for musculoskeletal pain because platelets are a rich source of growth factors that may be beneficial for healing3. [ … ]