Evans syndrome in the SARS-CoV-2 era: “springing up like mushrooms”

Abstract

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Osti and colleagues describe an elderly patient with Evans syndrome (ES), a rare entity characterised by an heterogeneous association and sequence of autoimmune cytopenias, namely autoimmune haemolytic anaemia (AIHA), immune thrombocytopenia (ITP) and, rarely, autoimmune neutropenia. The patient had been previously diagnosed with warm type AIHA concomitant with ITP and, 5 months later, experienced an AIHA relapse with evidence of cold reactive (and complement-activating) autoantibodies upon severe pneumonia during coronavirus disease 19 (COVID-19)1. [ … ]