Abstract

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The current treatment of haemophilia is based on replacement of the missing coagulation factor and this can be done when the bleeding actually occurs (on-demand therapy) or as part of a preventive approach (prophylaxis)1,2. Nowadays, prophylaxis of bleeding, involving the regular infusion of the deficient coagulation factor, represents the mainstay of haemophilia care. Indeed, its early implementation reduces the risk of joint bleeding and the resulting development of arthropathy, allowing patients to lead a life comparable to that of non-affected individuals. […]

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Authors

Massimo Franchini - Italian National Blood Centre, National Institute of Health, Rome; Department of Haematology and Transfusion Medicine, "Carlo Poma" Hospital, Mantua, Italy

Giancarlo M. Liumbruno - Department of Haematology and Transfusion Medicine, "Carlo Poma" Hospital, Mantua, Italy

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