The effective use of platelet-rich plasma (PRP) in treating a severe traumatic knee injury in a child with hemophilia A

Abstract

Platelet-rich plasma (PRP) is a therapy primarily used in orthopedics or dermatology to stimulate healing and promote tissue regeneration. There are rare cases in which it was used to treat traumatic injuries or wounds, but none in persons with hemophilia (PwH).

Our young patient was admitted to emergency hospital following a blade injury to the knee. The wound was initially sutured but not treated with a coagulation factor concentrate. Subsequently, it became infected after surgery. The infection was complicated by significant skin and subcutaneous tissue loss. PRP was used to promote tissue regeneration. Three additional applications after first treatment were needed to repair the injury. Tissue regeneration began immediately and was completed after two weeks. No further therapies were required, and the child was discharged.

PRP therapy is an interesting, safe, and effective approach for treating traumatic injuries in PwH. It could reduce recovery times and the need for clotting factor concentrates.