Rhnull blood type is characterized by the complete absence of Rh antigens on red blood cells, a condition that can lead to notable morphological abnormalities. In this study, a patient with an Rhnull phenotype was identified through serologic testing. Sequencing of RHAG revealed a novel c.640+1G>C mutation, which was subsequently confirmed to be inherited from the father and transmitted to the children.
Min Wang
- Department of Blood Transfusion, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China; Organ Transplant Center, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
Shuangshuang Jia
- Institute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, China
Shanshan Zhou
- Department of Blood Transfusion, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
Shihui Li
- Organ Transplant Center, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
Qian Liu
- Organ Transplant Center, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
https://orcid.org/0000-0002-7186-6536
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