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PLASTIC RECONSTRUCTIVE AND REGENERATIVE SURGERY

Abstract

We report the first case of a clinically significant delayed hemolytic transfusion reaction associated with anti-Aua antibody in an 18-year-old male with beta-thalassemia and pre-existing anti-D, -C, and -Jkb antibodies. Following transfusion with antigen-negative red blood cells, a new anti-Aua antibody was identified, confirmed by a positive Monocyte Monolayer Assay. These findings underscore the importance of vigilance in identifying rare antibodies that may impact transfusion strategies and advanced therapeutic options.

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Authors

Aleksander Luniewski - Department of Pathology, University of Virginia, Charlottesville, VA, United States of America

Courtney E. Lawrence - American Red Cross, Biomedical Services, Richmond, VA, United States of America

C. John Luckey - Department of Pathology, University of Virginia, Charlottesville, VA, United States of America

James D. Gorham - Department of Pathology, University of Virginia, Charlottesville, VA, United States of America https://orcid.org/0000-0003-3711-2607

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