Abstract

Automated Red Cell Exchange (RCE) using apheresis machines has been known since the 1980s. We implemented the IHD RCE strategy using SPECTRA OPTIA in mid-2021 during the Corona Viral Disease-19 (COVID-19) pandemic with the intention to decrease the number of PRBC units used, rather than increasing the time interval between sessions. This single-centre retrospective study demonstrated the sustainability of IHD over 2.5 years. While some patients required an increase in the number of PRBC units used at initiation, we demonstrated a durable 18.5% reduction in number of PRBC units used without any significant change in FCR at 2.5 years.

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Authors

Nikhil Vojjala - Department of Internal Medicine, Trinity Health Oakland/Wayne State University School of Medicine, Pontiac, MI, United States of America https://orcid.org/0000-0001-7238-1058

Rishab Prabhu - Department of Internal Medicine, Trinity Health Oakland/Wayne State University School of Medicine, Pontiac, MI, United States of America

Janaka SS Liyanage - Biostatistics and Bioinformatics Core, Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United States of America

Dipen Kumar Modi - Department of Hematology-Oncology Karmanos Cancer Institute/Wayne State University School of Medicine Detroit, MI, United States of America

Jay Yang - Department of Hematology-Oncology Karmanos Cancer Institute/Wayne State University School of Medicine Detroit, MI, United States of America

Andrew Kin - Department of Hematology-Oncology Karmanos Cancer Institute/Wayne State University School of Medicine Detroit, MI, United States of America https://orcid.org/0000-0002-3263-2374

Indryas Woldie - Department of Hematology-Oncology Karmanos Cancer Institute/Wayne State University School of Medicine Detroit, MI, United States of America

Asif Alavi - Department of Hematology-Oncology, Henry Ford Health System, Detroit, MI, United States of America

Vijendra Singh - Department of Hematology-Oncology Karmanos Cancer Institute/Wayne State University School of Medicine Detroit, MI, United States of America https://orcid.org/0000-0002-4898-5705

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