Blood Transfusion - 5 2016 (September - October)
Molecular immunohaematology round table discussions at the AABB Annual Meeting, Philadelphia 2014
Authors:  Willy A. Flegel, Shirley L. de Castilho, Margaret A. Keller, Ellen B. Klapper, Joann M. Moulds, France Noizat-Pirenne, Nadine Shehata, Gary Stack, Maryse St-Louis, Christopher A. Tormey, Dan A. Waxman, Christof Weinstock, Silvano Wendel, Gregory A. Denomme
Pages:  425-433
To cite this article:  Blood Transfus 2016; 14: 425-33
Doi:  10.2450/2015.0130-15
Published online:  21/12/2015

Use of molecular-based immunohaematology testing is becoming more widespread worldwide in laboratories that are accustomed to the use of blood group serology alone. Molecular immunohaematology issues may be challenging even for some established professionals in the field of blood group serology. At an international meeting, we offered round table discussions on four patient-related and two donor-related topics, which are current and possibly controversial. Six molecular immunohaematology questions were addressed: applications for highly contagious infections, such as Ebola; utility after transfusions in the preceding three months; root cause analysis for unexplained occurrence of anti-D; acceptable turnaround time for red cell genotyping of patients; criteria for donor cohorts to be genotyped; and quality assurance for discrepancies between  serological phenotype and licensed red cell genotyping. The opinions polled in this workshop with an international assemblage of more than 100 transfusion medicine specialists were discussed in the light of education and training opportunities and the development of guidance in the field. We provide a summary report of the participants' input to our questions and discuss the topics. [...]
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