Blood Transfusion - 4 2015 (October - December)
Procoagulant impact of the plasmapheresis procedure on coagulation state of collected plasma
Authors:  Stepan Surov, Ruzanna Ovsepyan, Igor Vysochin, Elena Kobzeva, Valeriy Khvatov, Mikhail Panteleev, Tatiana Vuimo
Pages:  651-655
To cite this article:  Blood Transfus 2015; 13: 651-5
Doi:  10.2450/2015.0315-14
Published online:  09/07/2015

Plasmapheresis is a group of extracorporeal techniques that involve removal of whole blood, separation of plasma from cellular elements and partial return of blood components (at least the red blood cells) into the circulation. It is widely used for therapy and plasma collection with the purpose of either further transfusion or manufacture of medicines. Plasmapheresis necessarily involves significant contact of blood with inner surfaces of the plasmapheresis kit, so the possibility of contact activation of coagulation is a concern with regards to both donor safety and quality of the product obtained. [... ]
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