Blood Transfusion - 4 2013 (October - December)
Spanish Consensus Statement on alternatives to allogeneic blood transfusion: the 2013 update of the "Seville Document"
Authors:  Santiago R. Leal-Noval, Manuel Muñoz, Marisol Asuero, Enric Contreras, José A. García-Erce, Juan V. Llau, Victoria Moral, José A. Páramo, Manuel Quintana, for the Spanish Expert Panel on Alternatives to Allogeneic Blood Transfusion
Pages:  585-610
To cite this article: 
Doi:  10.2450/2013.0029-13
Published online:  17/06/2013


Summary of recommendations on alternatives to reduce allogeneic blood transfusion (in descending order of strength)
Grade 1A recommendations

We recommend:
- The use of restrictive transfusion strategies in non-bleeding, euvolaemic anaemic patients.
- Perioperative administration of tranexamic acid to patients undergoing cardiac surgery.
- The administration of intravenous iron to cancer patients, as an adjuvant to erythropoiesis-stimulating agents, for correcting chemotherapy-induced anaemia.
- Preoperative administration of erythropoiesis-stimulating agents to anaemic, orthopaedic surgical patients expected to have moderate blood losses.
We do not recommend:
- The administration of desmopressin to patients undergoing elective surgery.
- The administration of erythropoiesis-stimulating agents to critically ill patients who do not have a previous indication for this therapy. (...)

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