Blood Transfusion - 1 2009 (January - March)
Recommendations for the transfusion of red blood cells
Authors:  Giancarlo Maria Liumbruno, Francesco Bennardello, Angela Lattanzio, Pier Luigi Piccoli, Gina Rossetti
Pages:  49-64
To cite this article:  Blood Transfus 2009; 7: 49-64
Doi:  10.2450/2008.0020-08
Published online:  19/08/2008

The transfusion of red cell concentrates (RCC) is indicated in order to achieve a fast increase in the supply of oxygen to the tissues, when the concentration of haemoglobin (Hb) is low and/or the oxygen carrying capacity is reduced, in the presence of inadequate physiological mechanisms of compensation (table I)1-14.
Tissue oxygenation depends on various factors
-       the concentration of Hb;
-       the saturation of Hb, which, in turn, depends on the O2 tension and the affinity of the Hb for O2;
-       the O2 requirement, that is, the volume of oxygen needed by the tissues to carry out their aerobic function. ..........................
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