Introduction
The transfusion of red cell concentrates (RCC) is indicated in order to achieve a fast increase in the supply of oxygen to the tissues, when the concentration of haemoglobin (Hb) is low and/or the oxygen carrying capacity is reduced, in the presence of inadequate physiological mechanisms of compensation (table I)1-14.
Tissue oxygenation depends on various factors
- the concentration of Hb;
- the saturation of Hb, which, in turn, depends on the O2 tension and the affinity of the Hb for O2;
- the O2 requirement, that is, the volume of oxygen needed by the tissues to carry out their aerobic function. ..........................