Blood Transfusion - 1 2017 (January - February)
Investigation of iron status in blood donors
Authors:  Tomislav Vuk, Karin Magnussen, Wim de Kort, Gilles Folléa, Giancarlo M. Liumbruno, Harald Schennach, Giovani Vandewalle, Veerle Compernolle, Natalia Masharova, Georgia Karakatsiani, Isabella Argyrou, Vít Rehácek, Gulara Khanirzajeva, Johanna Castrén, Bruno Danic, Rachid Djoudi, Geneviève Woimant, Markus M. Mueller, Constantina Politis, Stefania Vaglio, Anita Daugavvanaga, Edita Vilutyte, Jean-Claude Faber, Denise Borg-Aquilina, Peter van den Burg, Arlinke Bokhorst, Ryszard Poglód, Jolanta Antoniewicz-Papis, Mario Muon, Olivia L. Burta, Jana Rosochová, Polonca Mali, Miguel A. Vesga, Karin Schneider, Rut Norda, Nicky Anderson
Pages:  20-41
To cite this article:  Blood Transfus 2017; 15: 20-41
Doi:  10.2450/2016.0101-16
Published online:  07/09/2016

Transfusion of blood components is an irreplaceable form of treatment for many patients1. However, besides providing sufficient amounts of blood components of excellent quality, blood transfusion services should protect the safety of blood donors. Numerous studies have proven that iron deficiency is common in frequent blood donors, particularly women2-5. Determination of the haemoglobin concentration is a routine part of the donor selection process both in order to ensure adequate quality of red cell concentrates collected and to protect the potential donor's health. Indeed, low haemoglobin is globally the most common reason for deferral of prospective blood donors. Nevertheless, only cases of manifest low haemoglobin levels and imminent anaemia are detected using this approach. More sensitive tests are needed to assess depletion of iron stores, particularly in non-anaemic individuals, with ferritin measurements being used most frequently. [....]
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